Assessment 2
Question 2
Which of the following statements is correct?
Select one or more:
A. The oral polio vaccine (OPV) never causes paralysis in vaccinated children because the polioviruses in the vaccine have been inactivated. | |
B. Live attenuated vaccines may pose a risk to people whose immune system is deficient or suppressed. | |
C. Many live attenuated vaccines require strict adherence to the cold chain in order to maintain their efficacy. | |
D. Tissue cultures in which live attenuated vaccines are grown may become contaminated with other pathogens. | |
E. Live attenuated vaccines induce a weak immune response and therefore always contain adjuvants to enhance the immune response to the vaccine. | |
F. Inactivated vaccines are more immunogenic than live attenuated vaccines and a single dose usually produces long-lasting immunity. |
Answers B, C, and D are correct.
Answer A: Polio is among the five vaccines that are recommended by WHO are produced using Live attenuated vaccine technology: Tuberculosis (BCG), Oral Polio Vaccine, Measles, Rotavirus, Yellow Fever.
Answer E: Live attenuated vaccines stimulate an excellent immune response. Adjuvants are therefore not critical elements of them.
(To revise information on Live attenuated vaccines click here).