Assessment 2

Question 2

Which of the following statements is correct?

Select one or more:

A. The oral polio vaccine (OPV) never causes paralysis in vaccinated children because the polioviruses in the vaccine have been inactivated.
B. Live attenuated vaccines may pose a risk to people whose immune system is deficient or suppressed.
C. Many live attenuated vaccines require strict adherence to the cold chain in order to maintain their efficacy.
D. Tissue cultures in which live attenuated vaccines are grown may become contaminated with other pathogens.
E. Live attenuated vaccines induce a weak immune response and therefore always contain adjuvants to enhance the immune response to the vaccine.
F. Inactivated vaccines are more immunogenic than live attenuated vaccines and a single dose usually produces long-lasting immunity.

Answer

Answers B, C, and D are correct.

Answer A: Polio is among the five vaccines that are recommended by WHO are produced using Live attenuated vaccine technology: Tuberculosis (BCG), Oral Polio Vaccine, Measles, Rotavirus, Yellow Fever.

Answer E: Live attenuated vaccines stimulate an excellent immune response. Adjuvants are therefore not critical elements of them.

(To revise information on Live attenuated vaccines click here).