Assessment 3

For each of the following descriptions of an AEFI, decide what is the most likely cause by choosing the correct option from the drop-down list.

A.	The rate of thrombocytopenia following immunization with measles was found to be slightly higher than the background rate in the equivalent unvaccinated population.
B.	Several 13-year-old girls reported feeling sick and two fainted soon after being vaccinated against human papilloma virus (HPV) in a mass vaccination campaign at their school. All the affected girls recovered without further ill effects.
C.	Failure by the manufacturer to completely inactivate a lot of inactivated polio vaccine leads to cases of paralytic polio.
D.	Adverse reactions occurred after a nurse in charge of an outreach vaccination clinic used a vial of measles vaccine which she had reconstituted the previous day.
E.	A 10-week-old infant developed a high fever within 24 hours of receiving oral polio vaccine (OPV). Malaria was diagnosed in the infant shortly thereafter.

Correct answers:

A. Vaccine product related reaction.

B. Immunization anxiety related reaction.

C. Vaccine quality related reaction.

D. Immunization error related reaction.

E. Coincidental event.

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