Assessment 5
Question 5
The Global Advisory Committee on Vaccine Safety (GACVS) is the main advisory body to WHO on vaccine-related safety issues. Which of the following actions are in the remit of this committee?
Select one or more:
| A. Providing advice on vaccine safety alerts that may have a potential to cause, public concern. | |
| B. Develop standard case definitions for specific Adverse Events Following Immunization. | |
| C. Providing scientific advice on vaccine safety issues of potential global importance, for example on the use of BCG vaccine in immunocompromised individuals. | |
| D. Review key tools of WHO that support the investigation of adverse events following immunization, for example the WHO Information Sheets on Oberved Rates of Reactions of specific vaccines. | |
| E. Identify and analyse new adverse reaction signals from data submitted to the WHO global individual case safety report (ICSR) database. |
Answers A, C and D are correct.
Established in 1999 under WHO's Immunization Safety Priority Project, the Global Advisory Committee on Vaccine Safety (GACVS) advises WHO on vaccine-related safety issues and enables WHO to respond promptly, efficiently and with scientific rigour to vaccine safety issues of potential global importance. (http://www.who.int/vaccine_safety)
Answer B
The Brighton Collaboration develops of single standardized case definitions for specific AEFIs. It is an international voluntary collaboration of scientific experts, launched in 2000. It facilitates the development, evaluation and dissemination of high-quality information about the safety of human vaccines. (https://brightoncollaboration.org/public)
Answer E
The WHO Programme for International Drug Monitoring (PIDM) provides a forum for WHO Member States to collaborate in the monitoring of drug safety, and notably, the identification and analysis of new adverse reaction signals from data submitted to the WHO global individual case safety report (ICSR) database by member countries. (http://www.who.int/medicines/areas/quality_safety/safety_efficacy/
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