Pharmacovigilance centres

The AEFI surveillance functions of pharmacovigilance centres relate to the reporting and investigation of adverse events associated with vaccines as well as medicinal drugs. Many countries now operate a decentralized pharmacovigilance system, with a national pharmacovigilance centre functioning as the focal point for a network of regional and/or local centres. These may be located in a range of organizations, including relevant government departments, hospitals, academic environments, or hosted by a professional body such as a national medical association.

The provision of a high-quality information service to health workers is a basic task of pharmacovigilance centres. Continuous and appropriate educational activities improves knowledge, and stimulates and encourages health workers to report AEFIs.

National immunization technical advisory groups (NITAGs)

Evidence-based information is accessible to NITAGs via the online NITAG Resource Centre. It provides four dedicated services.

NITAG Resource Centre http://www.nitag-resource.org

The general objective of NITAGs is to guide national governments and policy-makers to develop and implement evidence-based, locally relevant immunization policies and strategies that reflect national priorities. They support national authorities and empower them to address issues associated with:

  • Vaccine quality and safety,
  • The introduction of new vaccines and immunization technologies.

NITAGs also serve to:

  • Reinforce the credibility of national vaccine and immunization policies,
  • Help governments and national immunization authorities to resist pressure from vested interest groups,
  • Enhance the ability to secure government or donor funding for immunization programmes encourage a more comprehensive approach to immunization policy that:
    • Considers the health of vulnerable populations,
    • Integrates various pre-existing vaccine-specific task forces.